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Teicoplanin is a glycopeptide antibiotic complex comprised of 6 main components (the most abundant being TA2-2), with different specific fatty acid moieties. It is produced by strain Actinoplanes teichomyceticus ATCC 31121. Developed for the treatment of serious Gram-positive infections, predominantly in hospitalized patients, teicoplanin has potent in vitro activity against Gram-positive bacteria and an excellent safety and tolerability profile. In particular, it targets infections caused by Staphylococci, the principal indication for vancomycin. Serious infections caused by Staphylococci include skin and soft tissue infections, bloodstream infections and osteomyelitis.
Parenti F, Beretta G, Berti M, Arioli V. Teichomycins, new antibiotics from Actinoplanes teichomyceticus Nov. Sp. I. Description of the producer strain, fermentation studies and biological properties. J Antibiot (Tokyo). 1978 Apr; 31(4):276-83. doi: 10.7164/antibiotics.31.276.